Status:
COMPLETED
L-PRF Plus Non Surgical Periodontal Treatment
Lead Sponsor:
Universidad de los Andes, Chile
Conditions:
Periodontitis
Eligibility:
All Genders
Phase:
NA
Brief Summary
Abstract: Background: Leucocyte and Platelet-Rich Fibrin (L-PRF) has shown to promote regenerative processes, even reporting antibacterial effect. The aim of this split-mouth clinical trial was to ev...
Detailed Description
Materials and Methods Study design and Patient Selection A split-mouth, randomized controlled clinical trial enrolling 13 patients (8 males and 5 females, mean age 52.3 ± 9.4 years) was set-up. The pa...
Eligibility Criteria
Inclusion
- age between 30 and 70 years old
- diagnosis of chronic periodontitis
- at least one bilateral periodontal pocket ≥ 6 mm
- healthy patients
Exclusion
- inability to comply with the study protocol
- receiving antibiotic therapy or non-steroidal anti-inflammatory drugs during the previous two months or using calcium channel blockers, phenytoin, cyclosporine, or any associated drug that might affect gingival tissue
- periodontal treatment during the previous 12 months
- auto-immune disorders (self-reported)
- requiring antibiotic prophylaxis before periodontal treatment; or requiring non-steroidal anti-inflammatory drugs for postoperative pain management after periodontal treatment
- smokers \>10 cigarettes
- pregnancy/lactation.
Key Trial Info
Start Date :
October 30 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 30 2020
Estimated Enrollment :
13 Patients enrolled
Trial Details
Trial ID
NCT04520438
Start Date
October 30 2019
End Date
May 30 2020
Last Update
August 26 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Universidad de Los Andes
Santiago, Chile, 7550000