Status:
COMPLETED
Analysis of Intestinal Defensin Expression in Acute GVHD
Lead Sponsor:
University of Freiburg
Conditions:
GVHD,Acute
Ulcerative Colitis
Eligibility:
All Genders
18-99 years
Brief Summary
This study has the aim to analyze intestinal expression of endogenous antimicrobial peptides in patients with acute GVHD. The expression will be compared to intestinal expression of defensins in patie...
Detailed Description
Acute graft-versus-host disease (GVHD) is a major cause of morbidity and mortality in patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT). Acute GVHD is characterized by compl...
Eligibility Criteria
Inclusion
- age ≥ 18 years
- diagnostic endoscopy was performed
- diagnosis results available
- written informed consent
- ability to understand the nature of the study and the study related procedures and to comply with them
Exclusion
- age \< 18 years
- gastrointestinal cancer
- lack of informed consent
Key Trial Info
Start Date :
September 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 30 2024
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04522843
Start Date
September 1 2018
End Date
October 30 2024
Last Update
December 18 2024
Active Locations (1)
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1
Medical Center University of Freiburg
Freiburg im Breisgau, Baden-Wurttemberg, Germany, 79106