Status:

UNKNOWN

Prediction of Vulnerable Plaque Using Coronary CT Angiography and Computational Fluid Dynamic in Acute Coronary Syndrome

Lead Sponsor:

Shanghai 10th People's Hospital

Conditions:

Acute Coronary Syndrome

Plaque, Atherosclerotic

Eligibility:

All Genders

18-75 years

Brief Summary

The aim of the PVCFD trial is to predict vulnerable plaque confirmed by OCT using coronary CT angiography and computational fluid dynamics in patients with acute coronary syndrome.

Detailed Description

Acute coronary syndrome(ACS)mainly includes unstable angina, non-ST-segment elevation myocardial infarction, and ST-segment elevation myocardial infarction, which is the leading cause of death around ...

Eligibility Criteria

Inclusion

  • 1)acute coronary syndrome was diagnosed according to universal definition of ACS; and 2) coronary CTA was completed before CAG; and 3) definitely culprit lesion can be recognized by CAG; 4) OCT was done to detect coronary atherosclerotic plaques confirmed by CAG.

Exclusion

  • 1\) Previous history stent implantation; 2) previous history of coronary artery bypass graft surgery; 3) ACS without clear culprit lesion; 4) poor image quality of coronary CTA for APC and CFD analysis; 5) myocardial infarction secondary to other reasons

Key Trial Info

Start Date :

September 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2022

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT04524117

Start Date

September 1 2020

End Date

December 1 2022

Last Update

August 24 2020

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