Status:
UNKNOWN
Prediction of Vulnerable Plaque Using Coronary CT Angiography and Computational Fluid Dynamic in Acute Coronary Syndrome
Lead Sponsor:
Shanghai 10th People's Hospital
Conditions:
Acute Coronary Syndrome
Plaque, Atherosclerotic
Eligibility:
All Genders
18-75 years
Brief Summary
The aim of the PVCFD trial is to predict vulnerable plaque confirmed by OCT using coronary CT angiography and computational fluid dynamics in patients with acute coronary syndrome.
Detailed Description
Acute coronary syndrome(ACS)mainly includes unstable angina, non-ST-segment elevation myocardial infarction, and ST-segment elevation myocardial infarction, which is the leading cause of death around ...
Eligibility Criteria
Inclusion
- 1)acute coronary syndrome was diagnosed according to universal definition of ACS; and 2) coronary CTA was completed before CAG; and 3) definitely culprit lesion can be recognized by CAG; 4) OCT was done to detect coronary atherosclerotic plaques confirmed by CAG.
Exclusion
- 1\) Previous history stent implantation; 2) previous history of coronary artery bypass graft surgery; 3) ACS without clear culprit lesion; 4) poor image quality of coronary CTA for APC and CFD analysis; 5) myocardial infarction secondary to other reasons
Key Trial Info
Start Date :
September 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2022
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04524117
Start Date
September 1 2020
End Date
December 1 2022
Last Update
August 24 2020
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