Status:
COMPLETED
Intraoperative Lidocaine and Combined With Ketamine on Opioid After Bariatric Surgery
Lead Sponsor:
Mahidol University
Conditions:
Laparoscopic Bariatric Surgery
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The most effective long-term treatment for obesity is bariatric surgery, however, postoperative pain control is challenging in these group of population. Opioid-sparing technique with multimodal analg...
Detailed Description
The prevalence of obesity and associated diseases have been increasing in recent decades. From 1980 to 2013, the number of adults with BMI more than 25 kg/m2 increased from 28.8% to 36.9% in men, and ...
Eligibility Criteria
Inclusion
- Adults patients age older than 18 years.
- Body mass index more than 30 kg/m2.
- Scheduled for laparoscopic bariatric surgery, including laparoscopic sleeve gastrectomy, robotic-assisted laparoscopic sleeve gastrectomy, laparoscopic Roux-en-Y gastric bypass surgery or robotic-assisted laparoscopic gastric bypass.
Exclusion
- Patient refusal.
- Inability to communicate or read in Thai language.
- Allergic to lidocaine or ketamine.
- History of opioid use within 2 weeks before surgery
- Cardiovascular disorder, including high grade atrioventricular block (second degree or third degree), history of coronary artery disease, poor controlled hypertension.
- History of stroke, intracranial hemorrhage or intracranial mass
- Cognitive impairment
- Schizophrenia or history of antipsychotic drugs
- Pregnant or breast-feeding patients
- Conversion to open surgery
Key Trial Info
Start Date :
April 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2025
Estimated Enrollment :
87 Patients enrolled
Trial Details
Trial ID
NCT04524130
Start Date
April 1 2021
End Date
January 31 2025
Last Update
May 9 2025
Active Locations (1)
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1
Faculty of medicine Siriraj hospital
Bangkok, Bangkok, Thailand, 10700