Status:

UNKNOWN

The Use of Triamcinolone Injection in Treatment of Refractory Benign Esophageal Stricture in Children

Lead Sponsor:

Assiut University

Conditions:

Esophageal Stricture

Eligibility:

All Genders

6-18 years

Phase:

PHASE4

Brief Summary

To evaluate the efficacy of Intra-lesional triamcinolone injection in the management of refractory benign esophageal Stricture in children.

Detailed Description

Oesophageal stricture is a commonly encountered clinical problem, especially in gastroenterology. It occurs due to narrowing of oesophagus, which results in swallowing difficulty. Oesophageal strictur...

Eligibility Criteria

Inclusion

  • All patients admitted to Assiut University Children Hospital with:
  • refractory benign esophageal stricture(inability to successfully remediate the anatomic problem to a diameter of at least 14 mm over five sessions at two-week interval)
  • inability to maintain a satisfactory luminal diameter for four weeks once the target diameter of 14 mm has been achieved

Exclusion

  • Pharyngeal stenosis precluding endoscopic examination and dilatation
  • tracheo-esophageal fistula,
  • gastric cicatrization that precluded safe placement of aguidewire
  • any patient who was unfit for general anesthesia.

Key Trial Info

Start Date :

December 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2022

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT04524897

Start Date

December 1 2020

End Date

March 1 2022

Last Update

October 27 2020

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