Status:

TERMINATED

Study of Descartes-30 in Acute Respiratory Distress Syndrome

Lead Sponsor:

Cartesian Therapeutics

Collaborating Sponsors:

National Heart, Lung, and Blood Institute (NHLBI)

Conditions:

Acute Respiratory Distress Syndrome

Covid19

Eligibility:

All Genders

18+ years

Phase:

PHASE1

Brief Summary

Emergency study to test the safety of Descartes-30 cells in patients with moderate-to-severe acute respiratory distress syndrome (ARDS) AND COVID-19

Eligibility Criteria

Inclusion

  • Patients must be 18 years of age or older at the time of enrollment
  • Patient maintains a diagnosis of moderate or severe ARDS according to the Berlin definition of ARDS

Exclusion

  • Patient is currently enrolled into another therapeutic clinical trial with an experimental therapy that has not received marketing approval by U.S. FDA.
  • Patient is in moribund state with expected survival \<24 hours.

Key Trial Info

Start Date :

February 23 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 9 2023

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT04524962

Start Date

February 23 2021

End Date

September 9 2023

Last Update

October 29 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

University of Iowa Hospitals and Clinics

Iowa City, Iowa, United States, 52242

2

University of Maryland Medical Center Medical Center

Baltimore, Maryland, United States, 21201