Status:
COMPLETED
MOIST Study: Multi-Organ Imaging With Serial Testing in COVID-19 Infected Patients
Lead Sponsor:
University of Alberta
Collaborating Sponsors:
Canadian VIGOUR Centre
Conditions:
Covid19
Coronavirus Infection
Eligibility:
All Genders
18+ years
Brief Summary
While many people with COVID-19 suffer from respiratory disease, there is growing evidence that the virus also affects other organs. The purpose of this study is to better understand the effects of CO...
Detailed Description
Participants with newly or recently diagnosed COVID-19 infection (inpatients and outpatients) will undergo multi-organ MRI (heart, brain, lungs, liver), blood work, and functional testing at one or mo...
Eligibility Criteria
Inclusion
- Troponin substudy
- 18 years of age or older
- Willing and able to provide informed consent
- COVID-19 positive test (within 14 days of positive test date)
- High-sensitivity Troponin-I \>100ng/L or Troponin T \> 52ng/L
- Ability to obtain Baseline MRI imaging within 7 days (up to 14 days maximum) of Troponin result
- Troponin substudy
Exclusion
- Contraindication to MRI or MRI contrast
- GFR \< 30ml/kg/min/1.73m2
- Hemodynamic instability requiring inotropic agents
- Active ventilatory support
- Late cross-sectional substudy Inclusion Criteria:
- 18 years of age or older
- Willing and able to provide informed consent
- Previously diagnosed with COVID-19 \> 3 months ago
- Ability to obtain MRI imaging at minimum 12 weeks from COVID-19 diagnosis
- Late cross-sectional substudy
Key Trial Info
Start Date :
November 12 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 30 2022
Estimated Enrollment :
215 Patients enrolled
Trial Details
Trial ID
NCT04525404
Start Date
November 12 2020
End Date
September 30 2022
Last Update
January 26 2023
Active Locations (2)
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1
University of Calgary
Calgary, Alberta, Canada
2
University of Alberta
Edmonton, Alberta, Canada