Status:
COMPLETED
Endothelial Function and COVID-19
Lead Sponsor:
Hospital San Carlos, Madrid
Collaborating Sponsors:
Mayo Clinic
Conditions:
COVID-19
Eligibility:
All Genders
Brief Summary
The present study aims to investigate the endothelial vasodilator function in patients with COVID-19
Detailed Description
Coronavirus disease 2019 (COVID-19), secondary to infection by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) has caused a global pandemic with significant adverse effects on the he...
Eligibility Criteria
Inclusion
- Study group No. 1: age ≥ 18 years; COVID-19 confirmed with positive PCR. Availability of informed consent.
- Study group No. 2: age ≥ 18 years; Past SARS-CoV-2 infection demonstrated by PCR and serology.
- Control group: age ≥ 18 years; absence of concurrent or previous SARS-CoV2 infection demonstrated by serology, and absence of acute or chronic diseases related to endothelial dysfunction, mainly acute or chronic infectious or inflammatory processes and known peripheral vascular disease.
Exclusion
- Impossibility of performing the endothelial function test.
- Recent puncture of the radial artery (\<15 days).
- Hemodynamic instability.
- Unavailability of signed informed consent.
Key Trial Info
Start Date :
June 3 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 11 2021
Estimated Enrollment :
110 Patients enrolled
Trial Details
Trial ID
NCT04525443
Start Date
June 3 2020
End Date
February 11 2021
Last Update
February 26 2021
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Mayo Clinic
Rochester, Minnesota, United States, 55905
2
Hospital Clínico San Carlos
Madrid, Spain, 28040