Status:

COMPLETED

Safety and Immunogenicity of 20vPnC Coadministered With SIIV in Adults ≥65 Years of Age

Lead Sponsor:

Pfizer

Conditions:

Pneumococcal Disease

Eligibility:

All Genders

65+ years

Phase:

PHASE3

Brief Summary

Study of the safety and immunogenicity of 20vPnC and influenza vaccine administered at the same visit or separately

Eligibility Criteria

Inclusion

  • Male or female participants ≥65 years of age at the time of consent
  • Adults determined by clinical assessment, including medical history and clinical judgment, to be eligible for the study, including adults with preexisting stable disease
  • Adults who have no history of ever receiving a pneumococcal vaccine, or have a history of receiving a licensed pneumococcal vaccination ≥6 months prior to first study vaccination.

Exclusion

  • History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis)
  • Previous vaccination with any investigational pneumococcal vaccine, or planned receipt of any licensed or investigational pneumococcal vaccine through study participation.
  • Vaccination with any influenza or pneumococcal vaccine \<6 months before investigational product administration, or planned receipt of any licensed or investigational non-study influenza vaccine during study participation.
  • \-- Serious chronic disorder, that in the investigator's opinion would make the participant inappropriate for entry into the study
  • Other acute or chronic medical or psychiatric condition or laboratory abnormality that may increase the risk associated with study participation or investigational product administration or may interfere with the interpretation of study results

Key Trial Info

Start Date :

September 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 29 2021

Estimated Enrollment :

1796 Patients enrolled

Trial Details

Trial ID

NCT04526574

Start Date

September 1 2020

End Date

June 29 2021

Last Update

July 8 2022

Active Locations (63)

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Page 1 of 16 (63 locations)

1

Alliance for Multispecialty Research, LLC

Mobile, Alabama, United States, 36608

2

East Valley Gastroenterology and Hepatology Associates

Chandler, Arizona, United States, 85224

3

Hope Research Institute

Phoenix, Arizona, United States, 85018

4

Paradigm Clinical Research Center

Redding, California, United States, 96001