Status:
COMPLETED
Mechanical Thrombectomy for Acute Large Vessel Occlusion Stroke With Mild Symptoms
Lead Sponsor:
Shanghai East Hospital
Conditions:
Ischemic Stroke
Acute Stroke
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Mechanical thrombectomy(MT) has been recommended in patients with acute large vessel occlusion stroke(LVO) , especially for those with National Institutes of Health Stroke Scale (NIHSS) score ≥6. Howe...
Detailed Description
This is a prospective cohort study of patients with with mild ischemic stroke (NIHSS Score \<6) and LVO. Patients were divided into 2 groups: MT or medical management.Baseline data and clinical outcom...
Eligibility Criteria
Inclusion
- acute ischemic stroke within 24 hours of symptom onset presenting cortical symptoms (such as aphasia, somnolence,slow-minded,etc.) or vertigo with bilateral pathological signs;
- age≥18 years old;
- the NIHSS score before evaluation of thrombectomy\<6;
- large artery occlusion including Middle cerebral artery M1, proximal M2 segment, intracranial internal carotid artery and infarct core volume≤50ml and mismatch ratio\>1.8 or basilar artery and posterior cerebral artery P1 occlusion
Exclusion
- Patients without prior functional independence (mRS score of \>2)
- Patients in intervention group with occlusive artery spontaneous recanalization in digital subtraction angiography
- patients in control group with neurological worsening and received rescue thrombectomy
Key Trial Info
Start Date :
July 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 20 2020
Estimated Enrollment :
105 Patients enrolled
Trial Details
Trial ID
NCT04526756
Start Date
July 1 2016
End Date
June 20 2020
Last Update
August 26 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Gang Li
Shanghai, Shanghai Municipality, China, 200123