Status:
COMPLETED
Impact of Amantadine on Traumatic Brain Injury
Lead Sponsor:
Damanhour University
Conditions:
Trauma, Brain
Eligibility:
All Genders
18-75 years
Phase:
PHASE4
Brief Summary
The aim of this study is to evaluate whether the addition of amantadine to the management regimen of traumatic brain injury patients would have a favorable effect on recovery and neurological complica...
Detailed Description
Proposal Steps 1. Approval will be obtained from Research Ethics Committee of Faculty of Pharmacy, Damanhour University. 2. All participants agreed to take part in this clinical study and provide inf...
Eligibility Criteria
Inclusion
- Inclusion criteria
- •Adult patients will be enrolled if they present with clinical signs of trauma brain injury
- Exclusion criteria
- Age lower than 18
- Females with positive pregnancy test
- Known congestive heart failure or ischemic heart disease
- Any injury disturbs the examination (high cervical cord injury or locked-in syndrome, could be a source of bias)
- Penetrating head trauma
- Need for any operation (laparotomy or craniotomy)
- Severe brain disease (For example CVA history or brain tumour)
- Renal failure with GFR lower than 60 ml/min
- Patients with unknown identity
Exclusion
Key Trial Info
Start Date :
September 30 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 30 2021
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04527289
Start Date
September 30 2020
End Date
October 30 2021
Last Update
April 7 2023
Active Locations (1)
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1
Tanta University Hospital
Tanta, Elgarbia, Egypt, 31527