Status:
COMPLETED
The Effect of 12-week Circuit Training on Insulin Sensitivity and Endothelial Function in Women With Insulin Resistance
Lead Sponsor:
Poznan University of Physical Education
Collaborating Sponsors:
Poznan University of Medical Sciences
Conditions:
Insulin Resistance
Eligibility:
FEMALE
25-45 years
Phase:
NA
Brief Summary
During the last 10 years many studies concerning the impact of physical training on whole-body insulin sensitivity have been published, but there is a lack of an extended investigation on the potentia...
Detailed Description
The training program will be performed on 7 machinesin a circuit. The devices will be controlled by a pre-programmed chip card, so that they will automatically adjust their parameters, such as seat he...
Eligibility Criteria
Inclusion
- women,
- age: 25-45years,
- menstruating,
- BMI 18,5-29,9 kg/m2,
- insulin resistance based on HOMA -IR (cut-off point 2.5),
- not contraindicated to physical activity.
Exclusion
- type 1 and 2 diabetes,
- poorly controlled hypertension (mean SBP \>140mmHg and/or mean DBP \>90mmHg) over the last month and/or need to modify the pharmacological treatment,
- obesity: BMI \> 30 kg/m2,
- lipid disorders requiring implementation of pharmacological treatment in the last 3 months before or during observation,
- a positive history of ischemic heart disease, carotid atherosclerosis and / or lower limb atherosclerosis,
- clinically significant arrhythmias or conduction disorders,
- chronickidney disease,
- clinically significant liver dysfunction,
- acute or chronic, clinically manifest inflammatory process,
- an acute infection in the last month,
- cancer,
- taking dietary supplements within a month before inclusion and during observation,
- taking medication that could interfere with the results of the tests,
- other conditions that may pose any risk to the patient during the observation.
Key Trial Info
Start Date :
August 17 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2025
Estimated Enrollment :
49 Patients enrolled
Trial Details
Trial ID
NCT04528693
Start Date
August 17 2020
End Date
June 30 2025
Last Update
September 23 2025
Active Locations (1)
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1
Poznan University of Physical Education
Poznan, Poland, 61-871