Status:
RECRUITING
A Developmental Framework For Linking Phonological And Morpho-syntactic Sequential Pattern Rules In DLD: Production
Lead Sponsor:
Father Flanagan's Boys' Home
Collaborating Sponsors:
University of Arizona
Conditions:
Developmental Language Disorder
Speech Sound Disorder
Eligibility:
All Genders
4-8 years
Phase:
NA
Brief Summary
The broad aim of this clinical study is to assess the hypothesis that morphological and phonological deficits are linked by a broader deficit in sequential pattern learning. This hypothesis applies to...
Detailed Description
The developmental approach taken here combines what is already known about morpho-syntactic deficits in DLD with recent developments in the fields of linguistics and language acquisition. First, it is...
Eligibility Criteria
Inclusion Criteria:
Because clinical precision is required, 4- to 8-year-olds will complete a large test battery.
- All children (TD, DLD, DLD + SSD, SSD) will score above 75 on the Nonverbal Scale of the Kaufman Assessment Battery for Children (KABC-II), which is above the Diagnostic and Statistical Manual cut-off for intellectual disability, even considering the standard error of measurement.
- Hearing will be within normal limits
- Oral structures will be within normal limits (Robbins & Klee, 1987).
- The Childhood Autism Rating Scale (Schopler et al., 2010) and parent report, will be used to rule out autism.
Children with DLD will meet standard criteria.
- Children with DLD will score below the cutoff of 87 on the Structured Photographic Expressive Language Test-P2 (SPELT-P2; Dawson et al., 2005) that has demonstrated high diagnostic accuracy for DLD.
- Children with DLD will perform below 80% in their spontaneous production of finite verb morphemes.
- Performance on a nonword repetition task will also support DLD status. Scores below 70% for total phonemes correct across all nonword lengths are greater than 1 SD below the mean for typical children.
- Speech production skills will be measured via the Goldman-Fristoe Test of Articulation-3 (GFTA-3; Goldman & Fristoe, 2015) and the inconsistency subtest of the Diagnostic Evaluation of Articulation and Phonology (DEAP, Dodd, et al., 2006). Many 4- to 6-year-old children with DLD are expected to perform below expected levels on the GFTA-3; for this study half of the children with DLD will show performance below expected levels and half above a standard score of 85. Children with SSD will show impaired performance on the GFTA-3, but typical performance on grammatically weighted language measures (SPELT-P2 and finite verb morphemes). The DEAP serves as a standardized measure of segmental inconsistency and will provide a post hoc analysis that may be related to sequence pattern variability.
Performance on the following measures will serve as covariates and will not be exclusionary for DLD or SSD:
- Peabody Picture Vocabulary Test, 4th ed (Dunn & Dunn, 1997)
- Expressive Vocabulary Test, 2nd ed (Williams, 1997)
- Verbal and nonverbal memory span.
- Because of the emphasis on English phonological and morpho-syntactic patterns, all participants will be monolingual English learners or report dominant exposure to English from infancy. Exposure to other languages will be documented.
Exclusion Criteria for all participants:
- Hearing impairment
- Intellectual impairment
- Autism
- Significant motor impairment.
Typical participants will be excluded if they show:
-Histories of developmental, speech, language, or hearing disorders.
Key Trial Info
Start Date :
August 7 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT04558541
Start Date
August 7 2022
End Date
December 31 2026
Last Update
October 27 2025
Active Locations (2)
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1
University of Arizona
Tucson, Arizona, United States, 85721
2
Boys Town National Research Hospital
Omaha, Nebraska, United States, 68131