Status:
RECRUITING
4D-MRI for Precision Medicine
Lead Sponsor:
University of Virginia
Collaborating Sponsors:
Duke University
The Hong Kong Polytechnic University
Conditions:
Healthy Volunteers
Liver Cancer
Eligibility:
All Genders
18-82 years
Brief Summary
The purpose of this study is to develop new ways to make medical images of the lungs and liver of adults using a technique called four-dimensional magnetic resonance imaging (4D-MRI). This technique p...
Detailed Description
Radiotherapy for cancer has been a forerunner of personalized medicine, developing individualized treatments based on patient-specific anatomical information. Despite many advances in radiotherapy ove...
Eligibility Criteria
Inclusion Criteria:The inclusion criteria for lung and liver cancer patients are:
- Patient is 21 or older
- Patient has primary or metastatic tumor(s) in the lungs or the liver
- Diameter of the tumor(s) is less than 7 cm
- Patient will receive radiation therapy (ordered by the treating Radiation Oncologist) as part of their treatment regimen
- Patient will undergo a planning CT scan with tumor motion assessment (planning 4D-CT ordered by the treating Radiation Oncologist) as part of their treatment regimen
- Patient has signed informed consent and is willing to comply with the 4D-MRI imaging protocol
The inclusion criteria for healthy volunteers are:
- Subject is 18 or older
- Subject has signed informed consent and is willing to comply with the 4D-MRI imaging protocol
Exclusion Criteria:
- Any condition for which a MRI procedure is contraindicated including presence of metallic material in the body, such as pacemakers, non- MRI compatible surgical clips, shrapnel, etc.
- Subjects who have difficulty lying flat on their back for extended periods of time
- Patients with any serious/poorly controlled medical or psychological conditions that would complicate protocol compliance
- Too large to adequately fit in the magnet bore or RF coils
- Claustrophobia
- Females who are pregnant or lactating
- Presence of active or chronic infection
Key Trial Info
Start Date :
November 5 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2030
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04657042
Start Date
November 5 2020
End Date
December 31 2030
Last Update
March 24 2025
Active Locations (1)
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1
University of Virginia
Charlottesville, Virginia, United States, 22908