Status:
UNKNOWN
Vitamin D Supplementation in Children With Sickle Cell Disease
Lead Sponsor:
Makerere University
Conditions:
Children With Sickle Cell Disease at Mulago Hospital
Eligibility:
All Genders
6-12 years
Phase:
NA
Brief Summary
Children aged 6 months to 12 years of age will be randomised to receive vitamin D 60,000IU once a month for 3 months or a placebo. The vitamin D will be in form of granules supplied in sachets. The pr...
Detailed Description
BACKGROUND: More than 75% of all children with sickle cell anemia (SCA) are born in sub-Saharan Africa annually. The hallmark of SCA is haemolytic anaemia and or pain crisis that often require hospita...
Eligibility Criteria
Inclusion
- Documented sickle cell disease (HbSS supported by hemoglobin electrophoresis results) attending Mulago Hospital Sickle Cell Clinic)
- Age range of 6 months to 12 years, inclusive, at the time of enrolment
- Weight at least 5.0 kg at the time of enrolment
- Willingness to comply with all study-related treatments, evaluations, and follow-up
Exclusion
- Known other chronic medical condition (e.g., HIV, malignancy, Renal \& liver disease, active clinical tuberculosis)
- Severe acute malnutrition determined by impaired growth parameters as defined by WHO weight for length/height less than -3SD.
- Evidence of Vitamin D supplementation in the past one month (by prescription or drug sample)
Key Trial Info
Start Date :
May 17 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 31 2022
Estimated Enrollment :
662 Patients enrolled
Trial Details
Trial ID
NCT04662476
Start Date
May 17 2021
End Date
January 31 2022
Last Update
April 13 2021
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.