Status:
COMPLETED
Exercise Hemodynamic, Right Ventricular Coupling and Echocardiography in Pulmonary Hypertension
Lead Sponsor:
University of Giessen
Conditions:
Hypertension, Pulmonary
Hypertension, Pulmonary Arterial
Eligibility:
All Genders
18+ years
Brief Summary
This study aims to investigate the exercise profile in pulmonary hypertension patients with either pulmonary arterial hypertension, chronic thromboembolic pulmonary hypertension or pulmonary hypertens...
Detailed Description
This is a dual-center observational prospective study in patients with pulmonary arterial hypertension, chronic thromboembolic pulmonary hypertension, pulmonary hypertension due to left heart disease....
Eligibility Criteria
Inclusion
- Confirmed diagnosis of pulmonary arterial hypertension (World Health Organization group 1)
- Pulmonary hypertension due to left heart disease (World Health Organization group 2)
- Chronic thromboembolic pulmonary hypertension (World Health Organization group 4)
- Invasive exclusion of pulmonary hypertension
- Age ≥ 18 years
- Planned right heart catheterization based on clinical grounds
- Stable specific PAH medications
- Ability to undergo cycle ergometry
- Signed informed consent
Exclusion
- Other etiologic groups of pulmonary hypertension (World Health Organization group 3, 5)
- Unstable or severe coronary artery disease
- Uncontrolled arterial hypertension
- Left ventricular ejection fraction \< 30%
- Severe congenital or acquired valvular or myocardial disease
- Progressive left heart failure
- History of severe ventricular arrhythmias
- Severe, terminal renal impairment
- Severe obstructive or restrictive lung disease
- Severe lung emphysema or interstitial lung disease
Key Trial Info
Start Date :
November 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 4 2023
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT04663217
Start Date
November 1 2020
End Date
November 4 2023
Last Update
May 17 2024
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Kerckhoff-Klinik
Bad Nauheim, Hesse, Germany
2
University of Giessen
Giessen, Hesse, Germany, 35390