Status:
COMPLETED
Isoenergetic High Intensity Interval Training and Moderate Intensity Training in Adults With Type I Diabetes
Lead Sponsor:
University of North Carolina, Chapel Hill
Collaborating Sponsors:
North Carolina Diabetes Research Center
Conditions:
Diabetes Mellitus, Type 1
Eligibility:
All Genders
18-51 years
Phase:
NA
Brief Summary
Type 1 diabetes (T1D) is associated with increased risk of poor cardiometabolic health. Regular exercise is recommended for optimal management of comorbidities in T1D. Unique barriers to exercise exis...
Eligibility Criteria
Inclusion
- Clinical diagnosis of presumed autoimmune T1D, receiving daily insulin
- Last hemoglobin A1c \<9%
- 18-51 years
- Duration of T1D: ≥ 1 year
- Body mass index (BMI) \<30 kg/m\^2
- Generally healthy, with no conditions that could influence the outcome of the trial, and in the judgement of the investigators is a good candidate for the study, based on a review of health history
Exclusion
- Physician diagnosis of active diabetic retinopathy that could be worsened by exercise
- Physician diagnosis of peripheral neuropathy with insensate feet
- Physician diagnosis of autonomic neuropathy
- Medications: beta-blockers, agents that affect hepatic glucose production such as beta adrenergic agonists, xanthine derivatives; any hypoglycemic agent other than insulin.
- Severe hypoglycemic event defined as the individual requiring a third party of hospitalization in the last 6 months
- Diabetic ketoacidosis in the last 6 months
- Has a closed-loop pump and not willing to use manual mode
- Physician diagnosis of cardiovascular disease that would affect exercise tolerance
- Currently doing HIIT
- Severely impaired hearing or speech
- Pregnancy
Key Trial Info
Start Date :
February 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 15 2022
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT04664205
Start Date
February 1 2021
End Date
September 15 2022
Last Update
July 26 2024
Active Locations (1)
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1
Applied Physiology Laboratory
Chapel Hill, North Carolina, United States, 27599