Status:
RECRUITING
Integrated Diagnostics for Early Diagnosis of Liver Disease
Lead Sponsor:
Manchester University NHS Foundation Trust
Collaborating Sponsors:
University of Manchester
University of Nottingham
Conditions:
Non-Alcoholic Fatty Liver Disease
Non-alcoholic Steatohepatitis
Eligibility:
All Genders
18+ years
Brief Summary
This is an observational study that will explore the hypothesis that by combining data from patients with liver disease with novel blood biomarkers, single nucleotide polymorphism (SNP) analysis and f...
Detailed Description
Liver disease is a silent epidemic. Four in ten people in the North West are likely to have evidence of liver disease. A small but significant proportion of these patients develop scarring, leading to...
Eligibility Criteria
Inclusion
- All patients referred to Community Liver Assessment Clinic.
- Male or female \> 18 years of age.
- Females will be non-pregnant and non-lactating.
Exclusion
- Age \< 18 years.
- Pregnancy/breast-feeding. Women of childbearing potential (not \>2 years post- menopausal and/or not surgically sterilised) must have a negative blood serum pregnancy test.
- Isolated bilirubinaemia.
- Known pre-existing liver disease.
- Acutely unwell.
- Suspected malignancy.
Key Trial Info
Start Date :
October 21 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2025
Estimated Enrollment :
1200 Patients enrolled
Trial Details
Trial ID
NCT04666402
Start Date
October 21 2020
End Date
April 1 2025
Last Update
March 27 2024
Active Locations (1)
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1
Manchester University NHS Foundation Trust
Manchester, Greater Manchester, United Kingdom, M13 9WL