Status:
UNKNOWN
The Effect of 3% Diquafosol Ophthalmic Solution on Visual Display Terminal-associated Dry Eye
Lead Sponsor:
Peking University Third Hospital
Conditions:
Dry Eye Syndromes
Computer Vision Syndrome
Eligibility:
All Genders
18-40 years
Phase:
PHASE4
Brief Summary
This study aims to evaluate the efficacy and safety of 3% Diquafosol Ophthalmic Solution for visual display terminal (VDT)-associated dry eye and to investigate the mechanism of treatment.
Detailed Description
The treatment period is 12 weeks. The day after subjects who meet the inclusion criteria undergo baseline examination is the day starting the medication. The dosing frequency was six times daily for 3...
Eligibility Criteria
Inclusion
- Male or female with a diagnosis dry eye based on Chinese Dry Eye Diagnosis Standard (2020)；
- Working in the offices with VDTs more than 4h daily；
- Working in the offices with VDTs at least five days per week；
- Provision of written informed consent.
Exclusion
- Known allergy to any eye drops
- Ocular therapies other than artificial tears
- Presence of any of the following conditions: active ocular infection, ocular inflammation, active ocular allergy, contact lens wear, ocular surgical history, laser treatment in the last 3 months, Meibomian gland dysfunction (MGD) over grade 2 (the grade is according to the report of the International Workshop on MGD in 2011), severe blepharitis or obvious inflammation of the eyelid margin, which in the judgment of the investigator may interfere with the interpretation of the study results
- Pregnant and lactating women, or those planning a pregnancy over the course of the study
- Uncontrolled systemic disease
- Hypersensitivity or intolerance to diquafosol(DQS)
- Subjects with a history of anxiety and depression
Key Trial Info
Start Date :
February 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 25 2023
Estimated Enrollment :
68 Patients enrolled
Trial Details
Trial ID
NCT04668118
Start Date
February 1 2021
End Date
March 25 2023
Last Update
June 1 2022
Active Locations (1)
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1
Peking University Third Hospital
Beijing, Beijing Municipality, China, 100191