Status:
TERMINATED
Comparing Different Sizes of Small-bore Chest Drains in Malignant Pleural Effusion
Lead Sponsor:
The University of Hong Kong
Conditions:
Pleural Effusion, Malignant
Lung Cancer Stage IV
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Malignant pleural effusion (MPE) is a very common medical condition, especially among patients with disseminated cancers. Chest drain insertion aims to drain the pleural fluid collection and relieve d...
Detailed Description
Introduction: Malignant pleural effusion (MPE) is the commonest complication of lung cancer, and its associated symptoms are frequent causes of hospitalizations and morbidities in patients with dissem...
Eligibility Criteria
Inclusion
- Patients who have cytologically/histologically proven pleural malignancy, or who have pleural effusion in the context of malignancy elsewhere
- The pleural effusion is at least moderate to massive and causes symptoms
- Ability to give informed written consent to the study
Exclusion
- Age \<18 years old
- Bleeding tendency not readily correctable (platelet \< 100 x 10\^9, INR ≥1.5 after transfusion)
- Hydropneumothorax before drain insertion
- Moderate-heavy septations in the pleural effusion (defined as a collection with more than 4 septations visible at the maximally septated area)
- Clinical emergency that an urgent chest drain is required
- Allergy to local anesthesia agents
- Blindness
- History of pleurodesis on the same side of malignant pleural effusion requiring drainage
Key Trial Info
Start Date :
December 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 30 2024
Estimated Enrollment :
52 Patients enrolled
Trial Details
Trial ID
NCT04669223
Start Date
December 1 2020
End Date
October 30 2024
Last Update
March 28 2025
Active Locations (1)
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1
Queen Mary Hospital
Hong Kong, Hong Kong