Status:
UNKNOWN
HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers
Lead Sponsor:
University of Calgary
Collaborating Sponsors:
University of Toronto
Université de Montréal
Conditions:
DIPG
Brain Tumor, Pediatric, Recurrent
Eligibility:
All Genders
2-21 years
Brief Summary
Although many children with brain tumours are successfully cured of their disease, a substantial proportion of patients suffer disease recurrence and require further treatment. This therapy may involv...
Detailed Description
Many children diagnosed with brain tumours are at significant risk of disease recurrence following their initial treatment, with recurrence rates ranging from 30-100% depending on the type of brain tu...
Eligibility Criteria
Inclusion
- Patient aged \>2 and \<21 years treated with a repeat course of radiation for DIPG or other recurrent or progressive brain tumour.
- Radiation for the first tumour must be a primary brain neoplasm (i.e. not leukemia).
- Enrollment within 14 days of starting re-irradiation (RT2).
- Patients with malignant transformation of the first tumour are eligible.
- There are no restrictions on histology or RT1/RT2 dose-fractionation or RT2 body site. In other words, RT2 may be directed at a different location to RT1.
- The patient is treated at a site where the study is approved by the local ethics board
- Consent, and, if applicable, assent, has been obtained according to institutional standards
Exclusion
- 1\. Inability to complete questionnaires in English or French.
Key Trial Info
Start Date :
July 2 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2023
Estimated Enrollment :
57 Patients enrolled
Trial Details
Trial ID
NCT04670016
Start Date
July 2 2020
End Date
December 1 2023
Last Update
November 10 2022
Active Locations (13)
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1
Alberta Children's Hospital
Calgary, Alberta, Canada, T3B 6A8
2
Stollery Children's Hospital
Edmonton, Alberta, Canada, T6G 2B7
3
British Columbia Children's Hospital
Vancouver, British Columbia, Canada, V6H 3N1
4
CancerCare Manitoba
Winnipeg, Manitoba, Canada, R3E 0V9