Status:

UNKNOWN

Ventricular Remodelling and Metabolomics in Pediatric Cardiomyopathies (PROGRESS-OMICS)

Lead Sponsor:

Bambino Gesù Hospital and Research Institute

Collaborating Sponsors:

Parent Project, Italy

Ministry of Health, Italy

Conditions:

Cardiomyopathies

Pediatric ALL

Eligibility:

All Genders

1-18 years

Brief Summary

The pathogenesis of cardiomyopathies is complex and a simple approach cannot describe the whole picture. Different etiologies are reported in pediatric age and heart failure onset can lead to poor pro...

Eligibility Criteria

Inclusion

  • Patients with Cardiomyopathies
  • Dilated Cardiomyopathy, defined as left ventricular dilation \> 2SD
  • A-D stages of Heart Failure, according to ACC/AHA definition
  • \< 18 years

Exclusion

  • Restrictive cardiomyopathy
  • Hypertrophic cardiomyopathy
  • Congenital Heart Diasease
  • Valvular Heart Disease, as primary cause of heart failure
  • \> 18 years
  • Control Group
  • Inclusion Criteria:
  • Children without familial disease and/ or abnormalities of ECG and echocardiographic, NT pro BNP ≥ 103 pg/mL, TnT ≥ 14

Key Trial Info

Start Date :

February 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2022

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04670731

Start Date

February 1 2021

End Date

June 1 2022

Last Update

February 10 2021

Active Locations (1)

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Bambino Gesù Hospital and Research Institute

Rome, Italy