Status:

UNKNOWN

Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment Syndrome

Lead Sponsor:

McGill University Health Centre/Research Institute of the McGill University Health Centre

Collaborating Sponsors:

United States Department of Defense

Hennepin Healthcare Research Institute

Conditions:

Acute Compartment Syndrome

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

The purpose of this trial is to conduct a pilot study that will aid in the design of an evaluation of the clinical benefit of MY01, an FDA cleared device, that allows continuous monitoring of intracom...

Detailed Description

Research Plan The purpose of this trial is to conduct a pilot study that will inform the design of a trial to evaluate the clinical benefit of MY01, a FDA cleared device that allows continuous monito...

Eligibility Criteria

Inclusion

  • Direct admission to hospital from scene of injury, or if transferred, admitted no more than 12 hours from injury
  • High-energy fracture of the tibial plateau (bicondylar or medial fracture - dislocation)
  • High energy displaced tibial diaphysis (highly comminuted or segmental fracture, or proximal third of tibia (e.g. GSW to the proximal fibula)) that is felt by the surgeon to have a likelihood of elevated ICP and risk of ACS.

Exclusion

  • Frankly contaminated or infected wounds or fractures.
  • Clinical suspicion of acute compartment syndrome requiring urgent fasciotomy at time of presentation to study center.
  • Monitoring could not be initiated within 12 hours of presentation
  • Acute or pre-existing neuropathy in the study limb.
  • Patient is pregnant
  • Patient is a prisoner/incarcerated

Key Trial Info

Start Date :

March 18 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 31 2023

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT04671173

Start Date

March 18 2022

End Date

March 31 2023

Last Update

April 12 2022

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Hennepin County Medical Center - Orthopaedic Research

Minneapolis, Minnesota, United States, 55414

2

Vanderbilt University Medical Center

Nashville, Tennessee, United States, 37232