Status:
COMPLETED
L-carnitine and COH in PCOS Women Undergoing IVF/ICSI Cycles
Lead Sponsor:
Royan Institute
Conditions:
Polycystic Ovary Syndrome
Eligibility:
FEMALE
20-37 years
Phase:
NA
Brief Summary
The aim of this study was to evaluate the effect of oral L-carnitine supplementation during controlled ovarian stimulation (COS) in patients with polycystic ovary syndrome (PCOS) in a double-blind ran...
Detailed Description
The study protocol was approved by the Institutional Review Board and Ethics Committee of Royan institute. Prior to the onset of ovarian stimulation, patients will be allocated randomly into two group...
Eligibility Criteria
Inclusion
- • Patients between 20 to 37 years old, presenting with primary or secondary infertility following regular intercourse for at least 1 year and diagnosed with polycystic ovary syndrome (PCOS) according to Rotterdam's criteria who had received two to three failures of IUI cycle therapy were included. The diagnosis was based on a complete history taking, physical examination and a paper documented complete infertility work-up within the previous 6 months
Exclusion
- Patients diagnosed with hyperprolactinemia, diabetes mellitus, epilepsy
- Patients treated with special diet, medication supplement (ovuboost), metformin before or during ovarian stimulation
- History of pelvic surgery on ovaries and uterus.
- Presence of submucosal and intramural fibroids larger than 5 cm or the presence of uterine polyps and congenital uterine malformations.
- The cause of severe male infertility (TESE, PESA).
Key Trial Info
Start Date :
March 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 28 2023
Estimated Enrollment :
110 Patients enrolled
Trial Details
Trial ID
NCT04672720
Start Date
March 1 2020
End Date
February 28 2023
Last Update
June 18 2023
Active Locations (1)
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1
Royan Institute
Tehran, Iran, 16635148