Status:

COMPLETED

Blood Flow Response and Acute INterval Exercise

Lead Sponsor:

University of Kansas Medical Center

Conditions:

Stroke

High Intensity Interval Exercise

Eligibility:

All Genders

18-80 years

Brief Summary

The objective of this project is to study the cerebrovascular response to a single bout of high intensity interval exercise (HIIT) in 25 individuals with chronic stroke compared to 25 age- and sex- ma...

Eligibility Criteria

Inclusion

  • Chronic Stroke
  • Age 40-80 years old
  • Treated for stroke 6 months to 5 years ago
  • Performs \<150 minutes of moderate intensity exercise per week
  • Able to answer consenting questions and follow a 2-step command
  • Chronic Stroke

Exclusion

  • Stroke etiology due to COVID-19 pathology.
  • Symptoms of COVID-19 and/or Positive COVID-19 test within the past 3 months
  • Unable to stand from a sitting position without physical assistance
  • Recent joint replacement/surgery/poor motor control that limits ability to perform exercise on a recumbent stepper
  • Insulin injection dependent diabetes
  • Dependent on supplementary oxygen
  • History of other neurological disease (Multiple Sclerosis, Alzheimer's disease, Parkinson's disease)
  • Unable to find TCD signal on the stroke-affected or non-affected MCA.
  • CON Inclusion Criteria:
  • Matched age ± 5 years to participant with chronic stroke
  • Matched sex to participant with chronic stroke
  • Performs \<150 minutes of moderate intensity exercise per week
  • Able to answer consenting questions and follow a 2-step command
  • CON

Key Trial Info

Start Date :

December 9 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 3 2023

Estimated Enrollment :

91 Patients enrolled

Trial Details

Trial ID

NCT04673994

Start Date

December 9 2020

End Date

February 3 2023

Last Update

February 9 2023

Active Locations (1)

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1

University of Kansas Medical Center

Kansas City, Kansas, United States, 66160