Status:
COMPLETED
BOne Dysfunction in Donor NEphrectomieS
Lead Sponsor:
Manchester University NHS Foundation Trust
Collaborating Sponsors:
University of Manchester
Conditions:
Renal Failure
Kidney Donors
Eligibility:
All Genders
18-80 years
Brief Summary
Most dialysis patients die from vascular disease, which is statistically associated with changes related to chronic kidney disease associated mineral bone disorder (CKD-MBD)3-9. Understanding the mech...
Detailed Description
The likelihood of five year survival for a 60 year old dialysis patient (50%) is significantly worse than for breast (88%), prostate (90%) or colon cancer sufferers (56%)1, but robust information abou...
Eligibility Criteria
Inclusion
- Potential living kidney donors who have completed the medical assessment and have been accepted for kidney donation. -
Exclusion
- Known to have a significant pathology that may influence markers of renal/bone axis - including but not limited to thyroid disorders, parathyroid disorders, amputees, Paget's disease, and severe osteoporosis.
- Previous treatment with bisphosphonates or denosumab.
Key Trial Info
Start Date :
July 29 2015
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2020
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT04674397
Start Date
July 29 2015
End Date
August 1 2020
Last Update
December 7 2021
Active Locations (1)
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1
Manchester University NHS Foundation Trust
Manchester, United Kingdom, M13 9WL