Status:
RECRUITING
iCorMicA - Stratified Medicine in Angina
Lead Sponsor:
NHS Greater Glasgow and Clyde
Collaborating Sponsors:
University of Glasgow
Abbott Medical Devices
Conditions:
Microvascular Angina
Angina, Stable
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The iCorMicA study is a multicentre, prospective, randomised, double-blind, sham-controlled, parallel-group, end-point trial and registry. The investigators seek to determine whether stratified medica...
Detailed Description
Ischaemic heart disease (IHD) includes coronary artery disease (or 'coronary heart disease 'CHD') and ischaemic with no obstructive coronary arteries (INOCA). Coronary angiography is standard care for...
Eligibility Criteria
Inclusion Criteria:
- Age ≥18 years.
- A clinical plan for invasive coronary angiography.
- Symptoms of angina (typical or atypical) according to the Rose- and/or Seattle Angina questionnaires.
- Able to comply with study procedures.
- Able to provide informed consent.
Exclusion Criteria:
- A non-coronary primary indication for invasive angiography (e.g. valve disease, heart failure).
- History of coronary artery bypass surgery.
- Presence of obstructive disease evident in a main coronary artery (diameter >2.5 mm), i.e. a coronary stenosis >50% and/or a fractional flow reserve (FFR) ≤0.80*.
- Logistical reason*. *These patients will enter a follow-up registry.
Key Trial Info
Start Date :
December 30 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2030
Estimated Enrollment :
1500 Patients enrolled
Trial Details
Trial ID
NCT04674449
Start Date
December 30 2020
End Date
December 31 2030
Last Update
April 9 2026
Active Locations (39)
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1
Mater Private Hsopital
Cork, Ireland
2
Mater Private Hospital
Dublin, Ireland
3
Radboud University Medical Centre
Nijmegen, Netherlands
4
5th Military Hospital
Krakow, Poland