Status:
UNKNOWN
Biomarkers in the Diagnosis of Acute Compartment Syndrome
Lead Sponsor:
University Hospital, Linkoeping
Collaborating Sponsors:
Medical Research Council of Southeast Sweden
Helsinki University Central Hospital
Conditions:
Acute Compartment Syndrome
Tibia Fracture
Eligibility:
All Genders
15-65 years
Brief Summary
This prospective multinational, multicentre cohort study aims to investigate the hypothesis that biomarkers of muscle cell damage can predict acute compartment syndrome in patients with tibial fractur...
Detailed Description
Patients with a tibial fracture are included. P-myoglobin and P-creatine phosphokinase are analysed at 6-hourly intervals pre- and if applicable, postoperatively after surgical fixation or fasciotomy....
Eligibility Criteria
Inclusion
- Tibial fracture group
- \- Traumatic tibial fracture
Exclusion
- Malignancy
- Acute myocardial infarction
- Kidney failure (GFR ≤35 ml/min)
- Muscle disease
- Paraplegia/tetraplegia
- Non-fracture group
- Inclusion Criteria:
- \- Suspected acute compartment syndrome
Key Trial Info
Start Date :
April 5 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2024
Estimated Enrollment :
250 Patients enrolled
Trial Details
Trial ID
NCT04674592
Start Date
April 5 2018
End Date
December 1 2024
Last Update
November 2 2022
Active Locations (1)
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1
University hospital of Linkoping
Linköping, Sweden, 581 85