Status:
COMPLETED
Pathological Findings of Fatal COVID-19
Lead Sponsor:
Nantes University Hospital
Collaborating Sponsors:
National Research Agency, France
Conditions:
SARS-CoV-2
Covid19
Eligibility:
All Genders
18+ years
Brief Summary
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new coronavirus discovered in December 2019 in Wuhan, China and currently responsible of a worldwide outbreak and the death of mor...
Detailed Description
Forty-four French ICUs participate to this study with the aim to perform 200 lung biopsies in 100 patients over a 12-month period. This cohort will be the largest pathological database of COVID-19 pat...
Eligibility Criteria
Inclusion
- Adult patients (Age≥18 years-old)
- Hospitalized in Intensive Care Unit (ICU)
- Dead in the ICU from documented Covid-19 (clinical and radiological signs of pneumonia with a positive SARS-Cov-2 PCR from the upper or lower respiratory tract)
- Not registered in the national register of refusal of the French Biomedicine Agency
- According to French law, there was no requirement for signed consent, but the patient's next of kin were informed about the study before enrolment and were given a letter of information about the study.
Exclusion
- Covid-19 not documented by a positive SARS-Cov-2 PCR
- Patient with a positive SARS-Cov-2 PCR but without any signs of pneumonia during the ICU stay (no clinical and no radiological signs of pneumonia)
- Patient registered in the "national register of refusal" of the French Biomedicine Agency
- Refusal expressed by the patient's next of kin to participate to the study
Key Trial Info
Start Date :
April 22 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 3 2021
Estimated Enrollment :
170 Patients enrolled
Trial Details
Trial ID
NCT04675281
Start Date
April 22 2020
End Date
March 3 2021
Last Update
November 30 2023
Active Locations (44)
Enter a location and click search to find clinical trials sorted by distance.
1
CH Amiens
Amiens, France
2
Angers University Hospital
Angers, France
3
CH Angoulême
Angoulême, France
4
CH Annecy
Annecy, France