Status:
COMPLETED
The Role of Mucosal Microbiome in Recurrence of Clostridioides Difficile Infection
Lead Sponsor:
Mayo Clinic
Conditions:
Clostridioides Difficile Infection
Eligibility:
All Genders
18+ years
Brief Summary
The study is being done to identify types of bacteria associated with the lining of the large intestine in people who have recently been treated for C. difficile infection to determine if there are fe...
Detailed Description
Patients who have recently been diagnosed with C. difficile infection and completed treatment will be enrolled to undergo evaluation of the colonic mucosa via sigmoid biopsies. Participants will also ...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Adults aged 18 and over
- Confirmed C. difficile infection based on positive C. difficile toxin PCR testing and clinical evidence of diarrhea
- Exclusion criteria:
- Known pregnancy
- Prior diagnosis of C. difficile infection within 2 months of this diagnosis
- Other known active gastrointestinal infectious process
- Known diagnosis of inflammatory bowel disease, microscopic colitis, celiac disease or other inflammatory conditions
- Vulnerable adults
- Any other disease(s), condition(s) or habit(s) that would interfere with completion of study, or in the judgment of the investigator would potentially interfere with compliance to this study or would adversely affect study outcomes.
Exclusion
Key Trial Info
Start Date :
September 23 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 5 2022
Estimated Enrollment :
52 Patients enrolled
Trial Details
Trial ID
NCT04675723
Start Date
September 23 2019
End Date
May 5 2022
Last Update
January 18 2023
Active Locations (1)
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1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905