Status:

COMPLETED

Total Neoadjuvant Therapy Versus Standard Therapy of Locally Advanced Rectal Cancer With High Risk Factors for Failure

Lead Sponsor:

Institute of Oncology Ljubljana

Conditions:

Rectal Cancer

Eligibility:

All Genders

18-99 years

Brief Summary

In a retrospective study, the investigators will compare patients with locally advanced rectal cancer with high risk factors for failure who were treated with standard therapy or with total neoadjuvan...

Eligibility Criteria

Inclusion

  • histologically proven locally advanced rectal cancer and
  • the presence of one of the factors: T4, N2, positive mesorectal fascia, presence of extramural vascular invasion or presence of lateral lymph node.

Exclusion

  • distant metastases,
  • concomitant malignancy,
  • inflammatory bowel disease, or
  • malabsorption syndrome.

Key Trial Info

Start Date :

January 1 2016

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2019

Estimated Enrollment :

161 Patients enrolled

Trial Details

Trial ID

NCT04679597

Start Date

January 1 2016

End Date

December 31 2019

Last Update

October 17 2024

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