Status:
COMPLETED
Deep Learning on 3D Cellular-resolution Tomogram
Lead Sponsor:
Mackay Memorial Hospital
Collaborating Sponsors:
National Taiwan University
Conditions:
Skin Diseases
Eligibility:
All Genders
20+ years
Brief Summary
Skin biopsy is the main method to diagnose skin tumors, skin inflammation, and pigmented diseases. However, biopsy is an invasive method that can cause wounds and scars. Optical coherent tomography (O...
Detailed Description
Introduction Optical coherent tomography (OCT) technology has been widely used in medical practice, such as ophthalmology. The application in dermatology is slowly progressed until the marked improvem...
Eligibility Criteria
Inclusion
- Inclusion criteria
- Experimental group:
- Adults aged 20 years or older
- Non-treat lesion of epidermal inflammatory disease: dermatitis and psoriasis
- Benign tumors: seborrheic keratosis and nevus
- Malignant tumors: actinic keratosis (AK), melanoma, basal cell carcinoma (BCC), Bowen's disease, squamous cell carcinoma (SCC), and extramammary Paget's disease (EMPD)
- Pigmented diseases: solar lentigo, melasma, and vitiligo
- Control group:
- The healthy face (exposed site) and inner forearm (unexposed site) skin of epidermal tumors and pigmented diseases of the above experimental group were used as a control group, excluding epidermal inflammatory diseases.
- Exclusion criteria
- Experimental group:
- Minors aged under 20 years
- Suspected a transcutaneous infectious disease, including infections such as bacteria, fungi, viruses, and parasites.
- All skin tumors that are in the subcutaneous tissue
- All skin lesions are open wounds
- All skin lesions are in a location that is difficult to scan
- Not willing to cooperate with methods and related procedures of this study
- Vulnerable populations, including prisoners, pregnant women, handicapped, mentally disabled, known AIDS patients, and homelessness
- Control group:
- Minors under 20 years of age.
- Epidermal inflammatory disease
- Suspected a transcutaneous infectious disease, including infections such as bacteria, fungi, viruses, and parasites.
- Individuals who have a systemic skin disorder.
- Individuals who have a history of severe skin condition
- Individuals with surgeries/cosmetic surgeries/micro cosmetic surgery (eg. cosmetic injections and/or laser etc.) on healthy skin at face and inner forearm in last 3 months and a physician determine the surgery will affect outcome of the OCT images.
- Not willing to cooperate with methods and related procedures of this study
- Vulnerable populations, including prisoners, pregnant women, handicapped, mentally disabled, known AIDS patients, and homelessness
Exclusion
Key Trial Info
Start Date :
December 21 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 14 2022
Estimated Enrollment :
107 Patients enrolled
Trial Details
Trial ID
NCT04679961
Start Date
December 21 2020
End Date
December 14 2022
Last Update
March 17 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Mackay Memorial Hospital
New Taipei City, Tamsui District, Taiwan, 25160