Status:
UNKNOWN
Comparison of Anesthesia Effects of Sevoflurane and Propofol Combined With Dexmedetomidine in Intraoperative Neuromonitoring During Thyroidectomy
Lead Sponsor:
Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Conditions:
Thyroid Nodule
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
According to the previous studies, it is reported that the use of sevoflurane in the maintenance of anesthesia may lead to delayed occurrence of positive electromyographic (EMG) signal and lower obtai...
Detailed Description
Recurrent laryngeal nerve (RLN) injury is one of the most serious common complications in thyroid operation. Compared with the traditional operation under direct eye vision alone, application of intra...
Eligibility Criteria
Inclusion
- patients scheduled for thyroidectomy under general anesthesia
- American Society of Anesthesiologists (ASA) grade of I or II
- aged 18 to 65 years
- body mass index (BMI) \< 32 kg/m2.
Exclusion
- patients with RLN or vagus nerve injury were identified preoperatively
- severe cardiovascular, pulmonary, liver and kidney diseases
- history of allergy to narcotic include rocuronium -pregnancy or lactation-
- history or current usage of medication which may interfere neuromuscular transmission;
- family or personal history of malignant hyperthermia
- myasthenia gravis
- potential risk of airway difficulty
- unable to cooperate.
Key Trial Info
Start Date :
April 30 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 31 2021
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT04680650
Start Date
April 30 2020
End Date
March 31 2021
Last Update
December 23 2020
Active Locations (1)
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1
Cancer Center of Guangzhou Medical University
Guangzhou, Guangdong, China