Status:

UNKNOWN

Molecular Taxonomy of Surgically-harvested Ocular Tissues Defined by Single-cell Transcriptomics

Lead Sponsor:

The First Affiliated Hospital with Nanjing Medical University

Conditions:

Diabetic Retinopathy

Proliferative Vitreoretinopathy

Eligibility:

All Genders

18-90 years

Phase:

NA

Brief Summary

The surgically-harvested eye tissue (ie. vitreous-retinal proliferative membrane, outflow pathway, retinas, and pterygium) is a complex tissue responsible for maintaining intraocular homeostasis or me...

Eligibility Criteria

Inclusion

  • Patients with ocular diseases and require surgery intervention.
  • The surgery intervention remove pathological tissue during surgery.
  • Patients consent to the treatment and single-cell sequencing.

Exclusion

  • 1\. Surgically removed eye tissue cannot meet with the quality control of single-cell sequencing (mainly the tissue weight and cell counts);

Key Trial Info

Start Date :

January 15 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2021

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT04682054

Start Date

January 15 2021

End Date

December 31 2021

Last Update

December 23 2020

Active Locations (1)

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1

First Affiliated Hospital of Nanjing Medical University

Nanjing, Jiangsu, China, 210029