Status:

COMPLETED

Effect of Metoclopramide Versus Erythromycin on on Gastric Residual Volume

Lead Sponsor:

Cairo University

Conditions:

Gastric Residual Volume

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

In emergencies, it may be necessary to anaesthetize who are not fully starved and consequently at risk of pulmonary aspiration. Pregnancy are recognized to be at increased risk of aspiration compared ...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Non-laboring pregnant women ≥36 weeks gestational age
  • Parturient scheduled for elective caesarian delivery.
  • Singleton pregnancy
  • Age greater than 18 years
  • Having followed institutional fasting guidelines (a minimum of 2 h for clear fluids, 6 h for a light meal, and 8 h for a meal that included fried or fatty food)
  • 2\. Exclusion criteria:
  • Refusal of the patient
  • Deviation from fasting times
  • Patients with empty stomach
  • Emergency operation
  • Body mass index (BMI) greater than 40 kg/m2
  • American Society of Anesthesiologists (ASA) physical status class III, IV.
  • Gestational diabetes mellitus
  • Multiple gestations
  • Patients with polyhydramnios liquor.
  • Preeclampsia patients
  • Chronic kidney disease patients
  • Systemic diseases may cause delayed gastric emptying (eg: myopathies and myasthenia gravis).
  • Patients with gastrointestinal diseases such as hiatus hernia, intestinal disease and gastro-oesophageal reflux disease and patients with history of upper gastrointestinal surgeries.
  • Patients on antidepressants and monoamine oxidase inhibitors
  • Use of other medications known to affect gastric motility or secretions.
  • Allergy to macrolide or metoclopramide

Exclusion

    Key Trial Info

    Start Date :

    March 1 2021

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    February 22 2024

    Estimated Enrollment :

    50 Patients enrolled

    Trial Details

    Trial ID

    NCT04682691

    Start Date

    March 1 2021

    End Date

    February 22 2024

    Last Update

    January 14 2025

    Active Locations (1)

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    1

    Faculty of Medicine, Cairo University.

    Cairo, Egypt, Egypt, 11451