Status:
UNKNOWN
Intraoperative Small-dose Esketamine Infusion for Pain Control in Burn Patients
Lead Sponsor:
Second Affiliated Hospital, School of Medicine, Zhejiang University
Conditions:
Burns
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This study aim to determine whether a small-dose esketamine infusion can be used for pain control in severe burn patients, and thereby reduce the total intra-operative opioid requirement. Secondary ob...
Eligibility Criteria
Inclusion
- All intubated adult burn patients( age\>18 ), presenting to the operating room;
- Burn area\> 30%.
Exclusion
- Allergy to Esketamine or benzodiazepines
- Esketamine or ketamine use in the preceding 24 hours
- Increased intracranial pressure
- Increased intraocular pressure
- Porphyria
- Thyroid disorders
- Seizures
- Acute myocardial ischemia
- Children (patients under age 18), prisoners, pregnant or breastfeeding women, patients with psychosis, patients with developmental delay, and any condition which, in the opinion of the investigator, would prevent full participation in this study or would interfere with the evaluation of the trial endpoints.
Key Trial Info
Start Date :
July 14 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2020
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT04682782
Start Date
July 14 2020
End Date
December 30 2020
Last Update
December 24 2020
Active Locations (1)
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1
2nd affiliated hospital, School of Medicine, Zhejiang Universtiy, China
Hangzhou, Zhejiang, China, 310003