Status:
UNKNOWN
The Establishment of a Survival Prediction Model for ER Positive / HER-2 Negative Advanced Breast Cancer
Lead Sponsor:
Ying Wang
Conditions:
Breast Cancer
Eligibility:
FEMALE
18-70 years
Brief Summary
This project is a prospective, clinical cohort study initiated by researchers to study the high-risk factors affecting the overall survival of newly diagnosed ER + / HER2 - advanced breast cancer pati...
Eligibility Criteria
Inclusion
- At the time of signing the informed consent form, 18 years old ≤ 70 years old, female
- ER positive breast cancer confirmed by pathology: ER positive (≥ 1%) by immunohistochemistry
- Newly diagnosed advanced patients, including patients with early breast cancer who have evidence of recurrence and metastasis after adjuvant therapy and patients with stage IV breast cancer at the first visit
- Patients who are willing to receive follow-up treatment in the research center.
Exclusion
- ErbB-2 gene amplification was recorded by fish (defined as HER2 / CEP17 ratio ≥ 2) or chromogenic in situ hybridization (CISH) or IHC (defined as ihc3 +, or ihc2 + confirmed by fish or CISH) was used to record HER2 positive tumors.
- Any form of anti-cancer treatment has been carried out for recurrent or metastatic lesions
- Combined with other malignant tumors or had other malignant tumors in recent 5 years
- Patients with nervous system disorders caused by diseases or obvious mental disorders will affect patients' right to know, compliance or make them in a dangerous state
- Patients with life expectancy less than 3 months
Key Trial Info
Start Date :
January 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
288 Patients enrolled
Trial Details
Trial ID
NCT04683757
Start Date
January 1 2020
End Date
December 31 2024
Last Update
December 24 2020
Active Locations (2)
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1
Sun Yat Sen Memorial Hospital，Sun Yat sen University
Guangzhou, Guangdong, China, 510000
2
Sun Yat-sen Memorial Hospital， Sun Yat-sen University
Guanzhou, Guangdong, China, 510000