Status:

COMPLETED

Effectiveness of Anti-VEGF Treatments in Wet AMD in Active Smokers

Lead Sponsor:

Brugmann University Hospital

Conditions:

Wet Age-related Macular Degeneration

Eligibility:

All Genders

18+ years

Brief Summary

" Wet Age-related Macular Degeneration (wet AMD)" is characterized by the appearance of new choroidal vessels. Several clinical studies have shown the effectiveness of intra-vitreous injections of ant...

Eligibility Criteria

Inclusion

  • CHU Brugmann Hospital patients
  • Patients who received three intra-vitreous injections of ranibizumab, aflibercept or bevacizumab 4 weeks apart as the first intra-vitreous treatment between January 2016 and December 2020.
  • Visual acuity measured before the start of the injections (maximum 1 month) and after the series of three injections (4 to 8 weeks after the last injection)
  • Patients whose smoking status is known and for whom the following history appears: hypertension, diabetes, taking anti-coagulants or anti-aggregants.

Exclusion

  • Patients who have already received another intravitreal treatment in the past.
  • Patients who have been treated with dynamic phototherapy before or at the same time as the injections.

Key Trial Info

Start Date :

November 10 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 28 2021

Estimated Enrollment :

148 Patients enrolled

Trial Details

Trial ID

NCT04685369

Start Date

November 10 2020

End Date

July 28 2021

Last Update

March 8 2022

Active Locations (1)

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CHU Brugmann

Brussels, Belgium, 1020