Status:
COMPLETED
Point of Care Optic Nerve Sheath Ultrasound to Assess Intracranial Pressure
Lead Sponsor:
Cairo University
Conditions:
Optic Nerve Sheath
Hypertonic Saline
Eligibility:
All Genders
18-60 years
Phase:
EARLY_PHASE1
Brief Summary
Elevated intracranial pressure (ICP) is one of the most common symptoms encountered in a variety of traumatic injuries and diseases. Any tissue swelling within the rigid confines of the skull results ...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Patients who having Isolated traumatized brain injury (not for surgical intervention)
- 3\<GCS ≤ 12.
- Both genders.
- Age ≥ 18 and ≤ 60Years.
- Physical status ASA I - III.
- Cut off value for optic nerve sheath diameter (ONSD) as 5.5 mm to diagnose increase in ICP\> 20 mm Hg.
- 2\. Exclusion criteria
- Patients' first-degree relatives' refusal to sign the consent.
- GCS (Glasgow coma score) \>12 or GCS of 3.
- Contraindication to hypertonic saline: pregnancy, coagulopathy and cardiac dysfunction.
- Spinal cord injury, orbital injury, optic nerve injury and optic neuritis.
- Multi organ affection.
- Serum Na level ≥ 150 mmol/L at admission to ICU.
- Hypotension requiring vasopressors to maintain MAP above 60 mmHg.
Exclusion
Key Trial Info
Start Date :
December 21 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 30 2021
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04686344
Start Date
December 21 2020
End Date
August 30 2021
Last Update
September 17 2021
Active Locations (2)
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1
Cairo university
Cairo, Egypt, 11451
2
Faculty of Medicine, Cairo University.
Cairo, Egypt, 11451