Status:

COMPLETED

The Effect of The Ten-Session Dual-tDCS On Lower-Limb Performance in Sub- Acute and Chronic Stroke

Lead Sponsor:

Mahidol University

Conditions:

Stroke, Ischemic

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

The present study aims to determine the effect of the ten-session dual tDCS combine with physical therapy on gait performance, balance, and lower limbs muscle strength in patients with subacute and ch...

Detailed Description

Stroke is a leading cause of long-term disability. The recovery of motor function after stroke is often incomplete, despite classical rehabilitation techniques. At the beginning of the 21st century, t...

Eligibility Criteria

Inclusion

  • Age range 20-75 years
  • First ever-ischemic lesion in the territory of middle cerebral artery or anterior cerebral artery. Diagnostic confirmation will be performed by CT scan or MRI
  • Sub-acute onset (1-6 months after the stroke onset) or Chronic (6 months - 5 years)
  • Able to walk without physical assistance at least 6 meters

Exclusion

  • Not cooperative or cannot understand the instruction
  • Clinical unstable such as vital sign unstable (systolic blood pressure (SBP) ≥ 185 mmHg or diastolic blood pressure (DBP) ≥ 110 mmHg (98) and resting heart rate averaging ≥ 100 bpm (99))
  • No clear neurological antecedent history or psychiatric disorder
  • Moderate pain in any joint of both lower limb (Pain Scale (VAS) ≥ 4/10)
  • Unstable medical conditions such as being in the middle of changing medical treatment.
  • Condition that may increase the risk of stimulation such as epilepsy, pregnancy, unexplained headaches, intracranial metal, pacemaker (evaluating by subjective examination).
  • Participate in the other protocol or receive alternative treatment such as transcranial magnetic stimulation within 1 month.

Key Trial Info

Start Date :

January 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2024

Estimated Enrollment :

34 Patients enrolled

Trial Details

Trial ID

NCT04687033

Start Date

January 1 2021

End Date

August 1 2024

Last Update

November 18 2025

Active Locations (1)

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Mahidol University

Nakhon Pathom, Thailand, 73170