Status:
UNKNOWN
Systemic and Peritoneal Inflammatory Response In Robotic-assisted And Laparoscopic Surgery for Colon Cancer
Lead Sponsor:
University of Southern Denmark
Collaborating Sponsors:
Region of Southern Denmark
Conditions:
Colonic Neoplasms
Colon Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The current hypothesis is that robotic-assisted surgery results in a reduced systemic and peritoneal inflammatory response (SIRS) compared to laparoscopic surgery in the treatment of colon cancer. The...
Eligibility Criteria
Inclusion
- Inclusion criteria
- Elective robotic-assisted or laparoscopic surgery for right-sided, left-sided and sigmoid colon cancer
- Aged ≥ 18
- ASA-score ≤ 3
- Tumor-stage (Tx-T4a)
- Endoscopic suspected colon cancer
- Histological verified adenocarcinoma, signet ring cell carcinoma, undifferentiated cancer, medullary carcinoma, or another malignant tumor type originating from colon
- Patients must give informed written consent
- Patients must be able to understand Danish language
- Exclusion criteria
- Carcinoma of the transverse colon or synchronous colorectal cancer
- Previous history of colon cancer
- Previous open major abdominal surgery with exception of open appendectomy and cholecystectomy.
- Metastatic disease
- Pregnancy
- History of psychiatric or addictive disorder that would prevent the patient from participating in the trial
- Emergency colon surgery
- Co-existing inflammatory bowel disease
- Co-existing immunological disease that requiring ingestion of systemic immunomodulatory drugs (DMARD - disease modifying anti-rheumatic drugs), corticosteroids and biologic disease-modifying anti-rheumatic drugs.
- Daily consumption of NSAID drugs
Exclusion
Key Trial Info
Start Date :
August 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04687384
Start Date
August 1 2021
End Date
September 1 2022
Last Update
June 16 2021
Active Locations (1)
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1
Hospital of Southern Denmark
Aabenraa, Denmark