Status:

COMPLETED

Validation of the Chinese Version of the SECONDs

Lead Sponsor:

Hangzhou Normal University

Conditions:

Minimally Conscious State

Vegetative State

Eligibility:

All Genders

16-75 years

Phase:

NA

Brief Summary

The aim of this study was to translate the SECONDs from English into Chinese and determine the validity of this Chinese version

Detailed Description

The assessment is of great importance for the management and treatment in patients with disorders of consciousness. The Simplified Evaluation of CONsciousness Disorders is a useful tool to assess cons...

Eligibility Criteria

Inclusion

  • age ≥ 16 years old;
  • no administration of neuromuscular blockers or sedation within the 24 hours of enrolment;
  • the presence of periods of eye opening (indicating wakefulness and rest cycles);
  • a diagnosis of VS or MCS, based on more than 4 times behavioral assessment performed using the Coma Recovery Scale-Revised within 2 weeks.

Exclusion

  • Coma;
  • documented history of prior brain injury;
  • psychiatric or neurologic illness;
  • neuromuscular blocking agents or sedative drugs administered within the prior 24 hours;
  • no documented history of a prior coma, critical illness or unstable medical condition;
  • upper limb contusions, fractures (based on the imaging examination) or flaccid paralysis (by using noxious stimuli to upper limbs, motor sub-scale scores \<1).

Key Trial Info

Start Date :

November 10 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2021

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT04687553

Start Date

November 10 2020

End Date

July 1 2021

Last Update

July 8 2022

Active Locations (1)

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1

International Vegetative State and Consciousness Science Institute, Hangzhou Normal University

Hangzhou, Zhejiang, China, 310036

Validation of the Chinese Version of the SECONDs | DecenTrialz