Status:
COMPLETED
The Effect of Intranasal Insulin on Motor and Non-motor Symptoms in Parkinson's Disease Patients
Lead Sponsor:
dr.dargahi
Conditions:
Parkinson Disease
Eligibility:
All Genders
17+ years
Phase:
PHASE2
Brief Summary
This study will evaluate the effect of intranasal insulin on motor and non-motor symptoms of patients with Parkinson's disease over a 12-week period.
Detailed Description
This study is a single-center, parallel and double-blind study. Patients with Parkinson's disease referred to Movement Clinic of Shohada-e-Tajrish Hospital will randomly receive intranasal placebo or ...
Eligibility Criteria
Inclusion
- Man and woman over 17 years old
- Patient with Parkinson's disease according to UK Parkinson's Disease Society Brain Bank Diagnostic Criteria
- Provide written informed consent to participate in the study.
- Understand that they may withdraw their consent at any time.
Exclusion
- Pregnant and lactating women
- Patients with diabetes and taking anti-hyperglycemic drugs
- Patients with other neurodegenerative diseases like multiple system atrophy, Huntington's, Wilson's disease, Alzheimer's, Amyotrophic lateral sclerosis (ALS), progressive supranuclear palsy, etc.
- Patients who cannot walk for more than one minute without help
- A history of allergic reaction to insulin
- The presence of inflammation of nasal cavity that may prevents absorption of insulin
Key Trial Info
Start Date :
January 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 20 2023
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT04687878
Start Date
January 1 2020
End Date
September 20 2023
Last Update
April 23 2024
Active Locations (1)
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1
Shahid Beheshti University of Medical Sciences, Shohada-e-Tajrish Hospital
Tehran, Iran