Status:

COMPLETED

Synovial Fluid Sleep Study

Lead Sponsor:

NYU Langone Health

Conditions:

Sleep

Eligibility:

All Genders

18+ years

Brief Summary

This is an observational study of the relationship between perioperative sleep time/quality, synovial fluid cytokine profiles, and clinical outcomes of primary ACL reconstruction with BPTB autograft i...

Eligibility Criteria

Inclusion

  • At least 18 years of age
  • Undergoing primary ACL reconstruction with BPTB autograft for acute ACL tear, with or without concomitant meniscectomy
  • Presenting within 2 weeks of injury and undergoing reconstruction within 8 weeks of injury

Exclusion

  • History of blood-borne diseases including HIV, HBV, HCV, HTLV, or syphilis
  • Pregnant
  • Multiligamentous knee injury
  • Concomitant meniscal repair, meniscal allograft transplantation, osteotomy, or repair of focal chondral defect (e.g., osteochondral autograft transfer system, osteochondral allograft, matrix-induced autologous chondrocyte implantation)
  • Prior ipsilateral knee surgeries or injuries
  • Primary sleep disorders including insomnia, sleep apnea, or restless legs syndrome
  • Uncontrolled psychiatric disorders with sleep disturbance
  • Night shift work
  • Travel with time zone change within three weeks of surgery
  • Systemic inflammatory disease
  • Autoimmune disease
  • Immunomodulatory drug use
  • Chemotherapy within a year before surgery
  • Intra-articular injection within 3 months before surgery

Key Trial Info

Start Date :

September 27 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 29 2024

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT04688099

Start Date

September 27 2021

End Date

March 29 2024

Last Update

May 30 2024

Active Locations (1)

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NYU Langone Health

New York, New York, United States, 10003