Status:
COMPLETED
Effects Magnesium Sulfate and Labetalol Infusion on Peripheral Perfusion and Pain in Nasal Surgeries
Lead Sponsor:
Zagazig University
Conditions:
Peripheral Perfusion
Postoperative Pain
Eligibility:
All Genders
21-45 years
Phase:
PHASE1
PHASE2
Brief Summary
One of main risk of controlled hypotension during nasal surgeries is impaired perfusion. Peripheral perfusion of non-vital organs usually impaired earlier than vital organs. So, evaluation of perfusio...
Detailed Description
To compare between the effects of magnesium sulfate and labetalol infusion during induced hypotension on peripheral perfusion and postoperative pain in nasal surgeries OBJECTIVES: To measure periphe...
Eligibility Criteria
Inclusion
- Written informed consent from the patient.
- Age: 21-45 years old.
- Sex: both sex (males or females).
- Physical status: ASA 1\& II.
- BMI = (20-30 kg/m2).
- Type of operations: elective nasal surgeries such as septoplasty, endoscopic sinus surgery and polypectomy.
- Duration of surgery ≤ two hours.
Exclusion
- Altered mental state
- Patients on beta blocker or with known history of allergy to study drugs.
- Advanced hepatic, renal, cardiovascular or respiratory diseases.
- Diabetic patients.
- Patients receiving anticoagulants or on pain killers.
Key Trial Info
Start Date :
February 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2021
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04688203
Start Date
February 1 2021
End Date
September 30 2021
Last Update
February 24 2022
Active Locations (1)
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1
Alshaimaa Abdel Fattah Kamel
Zagazig, Egypt, 002055