Status:
UNKNOWN
Motor Recovery Training for Hand and Digits in Stroke and SCI
Lead Sponsor:
Shirley Ryan AbilityLab
Collaborating Sponsors:
Johns Hopkins University
Conditions:
Acute Stroke
Cervical Spinal Cord Injury
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
This study will use evaluate a hand therapy device training isolated finger control with engaging video gaming technology to facilitate hand and digit recovery in patients with acute stroke and cervic...
Detailed Description
The purpose of this project is to develop a usable bedside hand therapy device that that takes advantage of early neuroplasticity following stroke and cervical spinal cord injury (SCI), to retrain fun...
Eligibility Criteria
Inclusion
- SCI patients
- Male and females between ages 18-75 years
- Within 1-2 months after traumatic SCI
- Cervical injury at C8 or above (tetraplegia)
- Categorized by the American Spinal Cord Injury Impairment Scale (AIS) as AIS A, B, C and D. Individuals with AIS A and B will be included if they score a minimum of 1 on the "Prehension Ability" GRASSP and are able to generate 0.01N with at least one finger in dominant or non-dominant hand using the Hummingbird device.
- Intact (level 2), impaired (level 1) or absent (level 0) lower motor neuron innervations in dermatomes C6, C7 and C8 during light touch and pin prick stimulus using the ISNCSCI sensory scores, and
- Stroke patients
- Males and females between ages 18-90 years
- Within 1 month after anterior circulation ischemic stroke
- Ability to score a minimum of 1 on the "Prehension Ability" GRASSP and are able to generate 0.01N with at least one finger in hemiparetic hand using the Hummingbird device.
- Ability to initiate elbow flexion and extension in hemiparetic arm with gravity removed.
- 6\. Ability to perform reaching movements towards an object at a 8 cm distance in front and above.
Exclusion
- SCI patients
- Uncontrolled medical problems including pulmonary, cardiovascular or orthopedic disease
- Any debilitating disease prior to the SCI that caused exercise intolerance
- Other neurological injury affecting target arm and hand
- Fracture or soft tissue injury to target arm and hand
- A pain scored greater than 3 on a 10 point scale at rest in target arm and hand
- Premorbid, ongoing major depression or psychosis, altered cognitive status
- History of head injury or stroke
- Ongoing cord compression or a syrinx in the spinal cord or who suffer from a spinal cord disease such as spinal stenosis, spina bifida or herniated cervical disk.
- Stroke patients
- Uncontrolled medical problems including pulmonary, cardiovascular or orthopedic disease
- Any debilitating disease prior to the stroke that caused exercise intolerance
- Other neurological injury affecting target arm and hand
- Fracture or soft tissue injury to target arm and hand
- Pain scored greater than 3 on a 10 point scale at rest in target arm and hand
- Premorbid, ongoing major depression or psychosis, altered cognitive status
- Inability to follow a three-step command.
Key Trial Info
Start Date :
October 20 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 27 2022
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT04688229
Start Date
October 20 2021
End Date
May 27 2022
Last Update
September 21 2021
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