Status:

RECRUITING

Microbiome in Cancer Patients With High Dose Chemotherapy With Stem Cell Transplantation

Lead Sponsor:

National Cancer Institute, Slovakia

Collaborating Sponsors:

Slovak Academy of Sciences

Conditions:

Hematologic Neoplasms

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Numerous in vitro and animal studies as well as growing number of clinical studies support the important role of microbiome in carcinogenesis and cancer treatment. Detection of changes in patients´ mi...

Detailed Description

Currently, available findings coming mainly from allo-HSCT (hhematopoietic cell transplantation) studies, link particular changes in microbiota with overall survival and post-transplant disorders, esp...

Eligibility Criteria

Inclusion

  • signed written informed consent
  • aged 18 years or older
  • patients planned to be treated by high-dose chemotherapy and hematopoietic cell transplantation or by CAR-T cell therapy in National Cancer Institute, Slovakia

Exclusion

  • \- patients not-matching inclusion criteria

Key Trial Info

Start Date :

March 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04691284

Start Date

March 1 2021

End Date

December 1 2026

Last Update

May 29 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

National Cancer Institute

Bratislava, Slovakia, Slovakia, 83310