Status:
UNKNOWN
Effect of Intermittent Hypoxia in Healthy Individuals
Lead Sponsor:
Shirley Ryan AbilityLab
Conditions:
Healthy
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The use of acute intermittent hypoxia (AIH) has been examined in animal and human studies to gain an understanding of its effect on spinal excitability and synaptic strength. Subsequently, the investi...
Detailed Description
The use of acute intermittent hypoxia (AIH), has been demonstrated, through human and animal studies, to be an effective way of increasing spinal motor excitability and strengthening residual synaptic...
Eligibility Criteria
Inclusion
- No history of neurologic injury or progressive neuromuscular disorder
- Individuals ages 18-70 years old
- Must be medically stable with no history of cardiovascular instability, congestive heart failure or stroke
- Not currently (\>2 weeks) on any medications related to spasticity
- No history of Sleep apnea
- Not a current smoker
- Able to comply with protocol/study requirements
Exclusion
- Recent change in the use of narcotic, anti-inflammatory or pain medication
- unstable medical conditions or any other clinical observation that may affect the candidate's performance, health, safety or the ability to participate in the study determined by the treating therapist or coordinating staff
- Active participation in another movement research study or therapy program
- Anti-spasticity drug injection less than 3 months prior to beginning treatment
- Musculoskeletal pain that interferes with participation in study
- Women who are currently, may be, or planning on becoming pregnant
- for fMRI participation, participants will be excluded if they have:
- Metal fragments in eyes or face
- Implantation of any electronic devices such as (but not limited to) cardiac pacemakers, cardiac defibrillators, cochlea implants, or nerve stimulators
- Vascular surgery
- Claustrophobia
- Body piercing or tattoos
Key Trial Info
Start Date :
November 16 2016
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT04691518
Start Date
November 16 2016
End Date
June 1 2024
Last Update
November 24 2023
Active Locations (1)
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1
Shirley Ryan AbilityLab
Chicago, Illinois, United States, 60611