Status:
COMPLETED
Electrophysiological and Neuroimaging Correlates of the Effect of Zolpidem in Patients With Focal Dystonia
Lead Sponsor:
University Medical Centre Ljubljana
Collaborating Sponsors:
Slovenian Research Agency
Clinical Centre of Serbia
Conditions:
Focal Dystonia
Eligibility:
All Genders
18+ years
Phase:
PHASE1
Brief Summary
To study electrophysiological and imaging correlations of the clinical effectiveness of zolpidem in task-specific dystonia and to elucidate mechanisms underlying its therapeutic effects, patients with...
Detailed Description
Background: The present view of dystonia is as of a circuit disorder, involving basal ganglia-thalamo-cortical and cerebello-thalamo-cortical pathways. One of the key pathophysiological features of dy...
Eligibility Criteria
Inclusion
- diagnosis of writer's cramp or musician dystonia
Exclusion
- Patients treated with botulinum toxin within the last 3 months
- Patients with contraindications for TMS
- Patients taking benzodiazepines, zolpidem or other sedative drugs 48 hours prior to the experiment
Key Trial Info
Start Date :
September 30 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 30 2021
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT04692285
Start Date
September 30 2017
End Date
April 30 2021
Last Update
December 4 2023
Active Locations (2)
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1
University Clinical Centre of Serbia
Belgrade, Serbia, 11000
2
Departmet of Neurology, University Medical Centre Ljubljana
Ljubljana, Slovenia, 1000