Status:
UNKNOWN
Study on the Clinical and Mechanism of Wenyang Huoxue Decoction in Treating Heart Failure After Myocardial Infarction
Lead Sponsor:
Jun Li
Conditions:
Heart Failure
Myocardial Infarction
Eligibility:
All Genders
18-75 years
Phase:
PHASE2
Brief Summary
This study is a randomized, double-blind, placebo-controlled, parallel clinical trial in a Chinese population with heart failure after myocardial infarction. The objective is to observe the efficacy a...
Detailed Description
Currently, there is a lack of high-quality evidence-based support for TCM treatment of heart failure after myocardial infarction. In addition, previous studies have found that the method of warming Ya...
Eligibility Criteria
Inclusion
- 18-75 years old;
- A history of acute myocardial infarction;
- Cardiac function grade II-IV;
- LVEF 40% or less; NT-proBNP level ≥ 450 pg/mL; -All men and women can sign the informed consent form.-
Exclusion
- Coronary artery bypass grafting was performed within 12 weeks.
- Undergo or possibly undergo cardiac resynchronization therapy;
- Primary valvular disease, left ventricular outflow tract obstruction, myocarditis, aneurysm, uncontrolled severe arrhythmia, cardiogenic shock, unstable angina pectoris, or acute myocardial infarction;
- Having a serious primary liver, kidney or blood system disease or having a serious mental illness or a systemic disease that is out of control;
- Serum creatinine \> 194.5 mol/L or serum potassium \> 5.5mmol /L;
- The level of alanine aminotransferase or alkaline phosphatase is 1.5 times of the normal upper limit ;
- Abnormal blood pressure control, systolic blood pressure exceeding 180mmHg or diastolic blood pressure exceeding 110mmHg;
- Pregnancy or lactation;
- Known or suspected allergy to research drugs;
- To receive another investigational drug within 30 days of randomization or to be unwilling or unable to provide written consent.
Key Trial Info
Start Date :
January 15 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2022
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04695990
Start Date
January 15 2021
End Date
December 30 2022
Last Update
January 6 2021
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.